(Iodomethyl)(triphenyl)phosphonium iodide - Names and Identifiers
(Iodomethyl)(triphenyl)phosphonium iodide - Physico-chemical Properties
Molecular Formula | C19H17I2P
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Molar Mass | 530.13 |
Melting Point | 260-266°C |
Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
(Iodomethyl)(triphenyl)phosphonium iodide - Risk and Safety
Hazard Symbols | Xi - Irritant
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Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin.
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Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S28 - After contact with skin, wash immediately with plenty of soap-suds.
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(Iodomethyl)(triphenyl)phosphonium iodide - Introduction
(Iodomethyl)(triphenyl)phosphonium iodide, chemical formula [(C6H5)3PI]I2, is an important organic phosphorus compound. Here are some information about its nature, use, formulation and safety:
Nature:
- (Iodomethyl)(triphenyl)phosphonium iodide is a colorless to pale yellow solid. It has a molecular weight of about 686.67g/mol.
-It is relatively stable at room temperature. However, at high temperatures or in contact with some incompatible substances, decomposition or explosion may occur.
Use:
- (Iodomethyl)(triphenyl)phosphonium iodide is commonly used as an electrophilic phosphorus reagent in organic synthesis.
-It can participate in many reactions, such as nucleophilic phosphorus substitution reactions of alkynes, iodophilic reactions of aldehydes and ketones, Michael addition, HWE enol phosphoketone synthesis, etc.
Method:
- (Iodomethyl)(triphenyl)phosphonium iodide is usually obtained by phosphorus treatment and substitution reaction. One common method of preparation is to react triphenylphosphine and methyl iodide with lithium iodide to give the product.
Safety Information:
- (Iodomethyl)(triphenyl)phosphonium iodide is a toxic substance and should be used and handled with appropriate safety measures.
-It has a stimulating effect on the eyes and skin, and direct contact should be avoided.
-Wear protective glasses, protective gloves and protective clothing during operation.
-When using or handling (Iodomethyl)(triphenyl)phosphonium iodide, it should be done in a well-ventilated place and avoid contact with oxidants or combustibles.
-When storing, keep it away from high temperature, open flame or sparks, and keep it sealed.
Please pay attention to the above information to ensure the safe use and handling of (iodomyl)(triphenyl)phosphonium iodide. The actual operation should follow the relevant laboratory safety regulations and operating guidelines. If necessary, consult a chemical expert or the relevant body for advice.
Last Update:2024-04-10 22:29:15